Oxycodone 80 mg is an extended-release opioid pain reliever of high dose that is used to treat severe, chronic pain that is not manageable by lower-dose opioids or other non-opioid measures. It is most typically available under brand names such as OxyContin and should not be taken on an as-needed or occasional basis. Because of its potency, it has a very high risk of overdose, addiction, and abuse, and should be used with great caution.
What Is It and How Does It Work?
Oxycodone is a strong opioid pain medication that affects the brain and spinal cord by binding to mu-opioid receptors. This action blocks the signals sent through the transmission of pain, changing the physical and emotional reaction to pain.
Key Features of the 80 mg Dose:
Extended-release (ER) form: formulated to slowly release the medication over 12 hours
Used exclusively in opioid-tolerant patients
Offers extended, around-the-clock pain relief
Should not be employed for breakthrough or acute pain
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Usages & Dosage
Indications:
Cancer pain
End-of-life (palliative) care
Severe, chronic back pain or neuropathic pain
Postoperative pain in opioid-tolerant patients
Standard Dosage:
Oxycodone ER 80 mg is typically administered every 12 hours.
It should be swallowed whole it is fatal to crush, chew, or split.
Reserve only for patients already on at least 60 mg morphine equivalent daily for one week or more.
Warning: Not for the opioid-naive patient because of high risk for fatal respiratory depression.
What If You Miss a Dosage?
If a dose is missed and it's less than 4 hours past due, take it as soon as you remember.
If it's later than 4 hours, miss the missed dose and continue on your regular schedule.
Never take more than one dose at a time; taking two doses can lead to respiratory failure or overdose.
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