The Global Preimplantation Genetic Testing (PGT) Market is expected to grow from USD 756.6 million in 2023 to USD 1,648.6 million by 2033, at a CAGR of 8.1%. This growth is driven by rising infertility linked to delayed parenthood, lifestyle factors, and environmental stressors, leading to increased reliance on IVF—where PGT enhances the chance of healthy pregnancies. Awareness of genetic disorders like Down syndrome and thalassemia is also encouraging at-risk couples to opt for PGT. Technological advancements have improved the accuracy and safety of testing, making it a standard part of fertility care. Additionally, supportive regulations and ethical guidelines have fostered public trust. The expansion of IVF clinics and improved healthcare infrastructure, particularly in emerging markets, is boosting accessibility. Public awareness campaigns and reduced stigma around assisted reproduction are further propelling demand, making PGT a key tool in modern reproductive healthcare.

Emerging Trends

1. Shift Toward Non-Invasive Testing: Instead of taking a sample directly from the embryo (which can be risky), scientists are now testing the fluid in which embryos grow. This safer method avoids harming the embryo and may become more common in fertility clinics.
2. Personalized Screening and Polygenic Testing: Genetic screening is becoming more personalized. Some new methods even try to predict an embryo's future risk for common diseases or traits by analyzing many genes at once. While this is still a developing area, it is gaining interest from both researchers and patients.
3. Rising Global Adoption: More fertility centers around the world, especially in developing regions, are starting to offer genetic testing before implantation. This shows growing awareness of the benefits of PGT in improving pregnancy outcomes.
4. Ethical and Legal Debates: As testing becomes more advanced, concerns are also rising. Questions about selecting embryos based on traits like intelligence or height are leading to ethical debates. Some countries are reviewing laws and guidelines to keep practices safe and fair.

Use Cases

1. Avoiding Hereditary Diseases: PGT is used to screen for genetic conditions that run in families. Parents who carry certain genes can use this test to avoid passing those conditions on to their children. This is especially helpful for couples who have experienced previous losses due to inherited diseases.
2. Improving IVF Success Rates: By testing embryos before they are implanted, doctors can choose ones with the right number of chromosomes. This increases the chances of a successful pregnancy and lowers the risk of miscarriage. It also helps reduce the need to transfer multiple embryos.
3. Helping Older Mothers or Those with Repeated IVF Failures: Women who are older or have had several failed IVF cycles can benefit from PGT. The test helps identify embryos with the best chance of leading to a healthy birth, which is especially important in these situations.
4. Testing for Multiple Genetic Traits: Some advanced tests now look at multiple genes to understand an embryo's future health risks. These tests may help parents make more informed decisions, although they are still being studied for long-term accuracy and usefulness.